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48 Hours in CDMX

Mexico City, or CDMX as locals call it, is a place where history, culture, and modern life collide in the most exciting ways. If you only have 48 hours in CDMX, you might feel overwhelmed by the sheer number of things to see and do. But with a well-planned itinerary, you can experience some of the city’s best highlights, from ancient ruins to vibrant neighborhoods and delicious food. I recently spent two days exploring this incredible city, and I’m excited to share a practical guide to help you make the most of your short visit.


Eye-level view of the Zócalo square with the Metropolitan Cathedral in the background
Zócalo square with the Metropolitan Cathedral, the heart of Mexico City

Day 1: Dive into History and Culture


Morning: Explore the Historic Center


Start your day early at the Zócalo, the massive main square in the heart of CDMX. This area is packed with history and stunning architecture. The Metropolitan Cathedral and the National Palace are must-sees. Inside the National Palace, you can admire Diego Rivera’s murals that tell the story of Mexico’s past.


Walk around the nearby streets to spot colonial buildings and lively markets. Don’t miss Calle Madero, a pedestrian street filled with shops and street performers. Grab a coffee and a traditional Mexican pastry at a local café to fuel up for the day.


Midday: Visit Templo Mayor and Lunch in Centro Histórico


Right next to the Zócalo, you’ll find the Templo Mayor, the ruins of the Aztec main temple. It’s a fascinating glimpse into the city’s pre-Hispanic roots. The museum there displays artifacts that bring the ancient civilization to life.


For lunch, head to Café de Tacuba, a historic restaurant known for its classic Mexican dishes and beautiful interior. Try the chiles en nogada if it’s in season, or the mole poblano for a rich, flavorful meal.


Afternoon: Stroll Through Alameda Central and Visit Museums


After lunch, walk to Alameda Central, a peaceful park surrounded by important cultural sites. Nearby is the Palacio de Bellas Artes, an architectural gem with impressive murals and art exhibitions. If you have time, visit the Museo Mural Diego Rivera to see one of his most famous works, Dream of a Sunday Afternoon in Alameda Park.


Evening: Dinner and Nightlife in Roma or Condesa


For your first evening, explore the neighborhoods of Roma or Condesa. Both areas are known for their trendy restaurants, bars, and vibrant street life. You can find everything from gourmet tacos to international cuisine.


I recommend trying El Parnita in Roma for authentic Mexican street food with a modern twist. After dinner, enjoy a mezcal cocktail at one of the local bars. These neighborhoods are perfect for a relaxed stroll with plenty of options for a nightcap.


High angle view of a colorful street in Roma neighborhood with cafes and trees
Colorful street in Roma neighborhood with outdoor cafes and greenery

Day 2: Nature, Art, and Markets


Morning: Chapultepec Park and Castle


Start your second day at Chapultepec Park, one of the largest city parks in the world. It offers a green escape from the urban rush. Visit the Chapultepec Castle, perched on a hill with panoramic views of the city. The castle houses a museum with historical artifacts and beautiful murals.


Take a walk around the park’s lakes and gardens. If you’re interested in art, the Museo Nacional de Arte Moderno and the Museo Tamayo are nearby and worth a visit.


Midday: Lunch at Mercado Roma


For lunch, head to Mercado Roma, a modern food market with a wide variety of stalls offering everything from tacos to craft beer. It’s a great place to sample different flavors and enjoy a casual atmosphere. Try the tacos al pastor or fresh ceviche.


Afternoon: Visit Coyoacán and Frida Kahlo Museum


Spend your afternoon in Coyoacán, a charming neighborhood with cobblestone streets and colonial architecture. It feels like a small town within the city. The main attraction here is the Frida Kahlo Museum, also known as the Blue House. It’s where the famous artist lived and worked, filled with her personal belongings and artwork.


After the museum, explore the local plazas and try some churros or coffee at one of the many cafés.


Evening: Dinner and a Walk in Polanco


Finish your 48 hours in CDMX with dinner in Polanco, an upscale neighborhood known for its high-end restaurants. Pujol is a world-renowned restaurant here, famous for its innovative Mexican cuisine. If you want something less formal but still delicious, try Quintonil or one of the many taquerias around.


After dinner, take a walk along Avenida Presidente Masaryk, Polanco’s main street, lined with shops and beautifully lit at night.


Tips for Making the Most of Your 48 Hours in CDMX


  • Use the Metro or ride-sharing apps to save time getting around.

  • Carry cash for markets and small vendors; not all places accept cards.

  • Stay hydrated and wear comfortable shoes; you’ll be walking a lot.

  • Learn a few basic Spanish phrases; locals appreciate the effort.

  • Be cautious with street food if you have a sensitive stomach, but don’t miss out on the authentic flavors.


 
 
 

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Send me an email to: ro@estoesmexico.mx

Address: Carretera México Toluca 1725 Local K8 Col. Campestre Palo Alto Cuajimalpa de Morelos CDMX CP 05119

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